BACTERIAL ‘DIE OFF’
Otherwise known as the Herxheimer Reaction…
‘Nature Outlook’ feature on the human microbiome.
“The trillions of microbes that live in and on our bodies could light paths to better health.” From faecal transplants to alcohol addiction, bacteriophages and anti-antibiotics, this collection of articles explores new understanding of the gut and how its microscopic world rules the health and wellbeing of humanity. https://www.nature.com/immersive/human-microbiome
The human brain has its own microbiome
Neuroscientists have been surprised to discover that the human brain is teeming with microbes, and we are beginning to suspect they could play a role in neurodegenerative disorders like Alzheimer’s… by David Robson.
Brain–gut–microbiota axis in depression
Depression is the most common mental disorder and a leading cause of disability worldwide. Despite abundant research, the precise mechanisms underlying the pathophysiology of depression remain elusive. Accumulating evidence from preclinical and clinical studies suggests that alterations in the gut microbiota, microbe-derived short-chain fatty acids, D-amino acids and metabolites play a key role in the pathophysiology of depression via the brain–gut–microbiota axis, including the neural and immune systems. Notably, the brain–gut–microbiota axis might play a crucial role in susceptibility versus resilience in rodents exposed to stress. Vagotomy is reported to block depression-like phenotypes in rodents after fecal microbiota transplantation of “depression-related” microbiome, suggesting that the vagus nerve influences depression through the brain–gut–microbiota axis. In this article, we review recent findings regarding the brain–gut–microbiota axis in depression and discuss its potential as a therapeutic target for depression.
Autism: stool sample diagnosis
Researchers found differences in the gut microbes of autistic people, raising hopes for faster diagnosis. By Ian Sample, Science Editor, The Guardian. 9 July 2024. Scientists have raised hopes for a cheap and simple test for autism after discovering consistent differences between the microbes found in the guts of autistic people and those without the […]
An interesting article on clinical outcomes
Role of the gut microbiota in nutrition and health. Ana M Valdes and colleagues discuss strategies for modulating the gut microbiota through diet and probiotics. Download